5 Easy Facts About Codeine Linctus Cough Syrup Described
5 Easy Facts About Codeine Linctus Cough Syrup Described
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Promethazine HCl and Codeine Phosphate Oral Solution needs to be applied with warning in patients with bone- marrow despair. Leukopenia and agranulocytosis are documented, normally when promethazine has been Utilized in Affiliation with other recognized marrow-harmful brokers.
A likely deadly symptom intricate from time to time known as Neuroleptic Malignant Syndrome (NMS) has actually been documented in Affiliation with promethazine HCl on your own or together with antipsychotic medications.
Extended-term usage of promethazine/codeine could have an effect on your ability to come to be pregnant or get a lover pregnant. Communicate with your healthcare service provider Should you have any considerations.
We wish to thank each of the patients, unbiased specialists and health industry experts who responded to our consultation.
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For those who have been taking promethazine/codeine routinely, tend not to halt having the drugs without speaking to your Health care company. Halting far too promptly may possibly result in really serious Unwanted effects. Simply call your healthcare company straight away When you have any of the next signs and symptoms.
Discontinuation of the concomitantly applied cytochrome P450 2D6 inhibitor may possibly lead to a decrease in codeine plasma focus and an increase in Lively metabolite morphine plasma concentration which could maximize or extend adverse reactions and could lead to possibly lethal respiratory depression.
This is referred to as adrenal website insufficiency. Adrenal insufficiency can worsen if Your system is less than strain thanks to fever, surgery, or trauma. Explain to your Health care service provider When you've got any of the subsequent indications of adrenal insufficiency.
Codeine may possibly enhance the neuromuscular blocking action of skeletal muscle relaxants and develop an increased diploma of respiratory depression.
Breathing complications (respiratory despair)that may result in Demise and opioid withdrawal can take place if you start having or halt getting other medicines whilst taking Promethazine Hydrochloride and Codeine Phosphate Oral Alternative, which get more info include:
Although the possibility of dependancy in any person is unidentified, it could happen in patients correctly prescribed Promethazine HCl and Codeine Phosphate Oral Option. Habit can take place at suggested dosages and check here if the drug is misused or abused. Challenges are elevated in people with a personal or spouse and children historical past of substance abuse (which include drug or alcohol abuse or dependancy) or psychological disease (e.g., major melancholy).
常見之不良反應有：瘙癢、噁心、嘔吐、昏睡、口乾、瞳孔縮小、姿態性低血壓（orthostatic hypotension）、小便不暢、便秘。
Promethazine/codeine is often utilised to lower coughing along with other signs or symptoms from allergy symptoms or typical click here cold.
No evidence of tumorigenicity was observed in male and feminine mice at codeine dietary doses approximately four hundred mg/kg/working day (about such as forty check here five situations the MRHD with a mg/m2 foundation).